San Bruno is a smaller residential market in North San Mateo County with approximately 45,000 residents. Its proximity to San Francisco International Airport and the Shops at Tanforan supports steady local and regional activity. Medical office space is concentrated along El Camino Real and near the San Bruno BART station, while occupancy costs are generally more affordable than in San Francisco or the central Peninsula. This makes San Bruno a practical option for primary care, urgent care, and specialty practices serving the surrounding community.